PN Healer 2ml standalone
Salmon-DNA polynucleotide alone. 3-session course. Skin-quality response over 8-12 weeks. SGD 600 per session.
PB HEALER + DR SAMANTHA'S LAYERED PROTOCOL
Rejuran Healer alone is rarely enough. We layer it into Signature Glow.
Rejuran Healer is the polynucleotide core of Dr Samantha's custom skin booster. One 2ml syringe is the building block. Full results come from mixing it with hyaluronic acid and bioactives, not from injecting it alone.
From SGD 500 per session
TREATMENT MENUSGD 500SGD 600SGD 600SGD 650SGD 800SGD 1300SGD 1500
Pricing for every variant.
PN I (under-eye, 1ml)
PN Healer 2ml
Teosyal Redensity 1 (1ml)
Signature Glow Booster Eye
Nucleofill Strong 1.5ml
Signature Glow Booster (face)
Nucleofill Strong 3ml
What polynucleotide booster protocols can address at Nexus
What one 2ml syringe of Rejuran Healer polynucleotide booster actually does
Rejuran Healer is a salmon DNA polynucleotide injectable, also called PDRN (polydeoxyribonucleotide). The polynucleotide fragments signal fibroblast activity in the dermis, stimulating collagen and elastin production over 8 to 12 weeks. It works at the dermal layer that topical actives cannot reach.
- Polynucleotide fragments: signal fibroblast activity. Result builds over 8-12 weeks across a standard 3-session course at monthly intervals.
- Salmon DNA derived: low immunogenicity profile in the established PDRN polynucleotide booster literature.
- Dermal-layer placement: shallow injections across the face surface. Not a volumiser, not a filler.
- Standard 3-session course: 4 weeks between sessions. Maintenance every 4-6 months thereafter.
PN Healer alone is good for skin-quality response. For patients who want more visible glow + texture change, Dr Samantha layers PN Healer with amino acids and peptides in her Signature Glow Booster mix.
Why the black box formulation matters for polynucleotide stability
Dr Samantha's preference is the Signature Glow Booster (layered PB + amino acids + peptides). Standalone PN Healer is offered when patients specifically want the polynucleotide booster alone protocol or want to start with the base-level option.
Why a polynucleotide booster base works better in combination than solo
Both share the same polynucleotide base. The difference is what gets layered on top.
- PN Healer alone: salmon-DNA polynucleotide only. Stimulates fibroblast activity, modest skin-quality response over 3 sessions. SGD 600 per session.
- Signature Glow Booster: PN Healer base + amino acids + peptides + a hydration layer. Same 3-session course. SGD 1,300 per session. Visibly more glow + texture response under Dr Samantha's protocol.
- Cost comparison over 3 sessions: PN Healer 2ml SGD 1,800 (3-session course). Signature Glow SGD 3,900. The price gap reflects the additional ingredients + the layered injection technique.
Polynucleotide booster dosage by area and how many 2ml syringes you need
Suitable for
Suitable for
- Patients with dehydrated, dull skin and early texture concerns.
- Patients comfortable with a 3-session monthly course and 8-12 week result window.
- Patients open to the Signature Glow upgrade once they understand the standalone-vs-layered difference.
- Patients with post-acne textural concerns benefiting from polynucleotide repair signalling.
Take care
Pause first
- Patients expecting volume change. PN Healer is dermal-quality, not a volumiser.
- Patients seeking same-day visible results. The polynucleotide response builds over 8-12 weeks.
- Patients with salmon allergy. Source ingredient is salmon-DNA-derived.
- Active inflammatory acne. Settle the skin first.
Why visible PN polynucleotide booster results show in one to two weeks
- Step 1, 10 min
Skin assessment + protocol confirm
Dr Samantha reviews dermal hydration, texture, recent treatments. Confirms PN Healer standalone vs Signature Glow Booster mix.
- Step 2, 5 min
Numbing cream + skin prep
Topical anaesthetic across the face. Skin cleaned with sterile prep.
- Step 3, 15-20 min
Dermal injection
Fine-needle injections across the face surface. Multiple small placements per cheek + forehead + chin. Minimal discomfort.
- Step 4, 5 min
Cool down + aftercare brief
Cool compress on injection points. Dr Samantha walks through 48-hour aftercare and session 2 booking 4 weeks out.
How long Rejuran Healer polynucleotide booster results actually last
PN Healer course at Nexus
| Concern | Typical sessions | Interval | Duration of results |
|---|---|---|---|
| PN Healer standalone full course | 3 sessions | 4 weeks apart | Result visible 8-12 wks; lasts 4-6 months |
| Signature Glow Booster full course | 3 sessions | 4 weeks apart | More visible glow + texture; lasts 5-7 months |
| Maintenance after first course | 1 per cycle | Every 4-6 months | Re-engages the polynucleotide response |
| PN I (under-eye) | 3 sessions | 4 weeks apart | 4-6 months under-eye tone improvement |
Maintenance cadence is matched to skin response, not a fixed package.
Rejuran Healer side effects and recovery to expect
Worth knowing
Common (most patients)
- Small bumps at each injection point for 24-48 hours, resolving as the booster spreads.
- Mild redness for 30-60 min post-session.
- Mild tenderness at injection sites for 24 hours.
Take care
Less common
- Localised bruising at one or two injection points, resolving within 5-7 days.
- Mild dryness for 24-48 hours, settles with hydration.
- Rare hypersensitivity. Patients with salmon allergy should not have polynucleotide protocols.
Rejuran Healer pricing context in Singapore
Rejuran Healer pricing in Singapore typically sits in the SGD 500 to SGD 700 per 2ml session range, with most clinics recommending a three-session course four weeks apart. Current per-session pricing at Nexus is shown in the treatment menu above. Polynucleotide injectables are not Medisave-claimable in Singapore.
Aftercare for a polynucleotide booster session
- Day 0 to 2
Settle the injection points
Avoid pressure on the face for 24 hours. No facials, no makeup over injection points for 12 hours. Cool compress for 10 min if any tenderness.
- Day 0 to 7
Restore the barrier
Sunscreen SPF 50 daily. Hyaluronic acid + ceramide moisturiser. Skip retinoids + vitamin C serums + exfoliants for 7 days.
- Week 4 onward
Session 2 booking
Book session 2 four weeks after session 1. Full polynucleotide response builds over 8-12 weeks across the course.
Esther sends a brief aftercare summary via WhatsApp post-session.
Why Rejuran Healer sits in Dr Samantha's protocol menu
- Polynucleotide-specific protocol: separate from HA-based skin boosters. Different mechanism, often layered with HA work for complementary effect.
- 3-session course with a defined endpoint, not an open-ended package.
- Standalone vs Signature Glow choice: transparent at consultation. Patients on tighter budgets start standalone; patients prioritising result upgrade to the layered mix.
- Combinable with Pico Laser for acne-scar work in a layered protocol.
- Established polynucleotide booster category with a long track record in Singapore aesthetic practice.
Common questions before booking
YOUR CONSULTATION
One assessment with Dr Samantha.
Twenty minutes with Dr Samantha. Consultation SGD 80, fully credited toward any treatment that follows.
111 Somerset Road, #03-19, TripleOne Somerset, Singapore 238164
Mon to Fri 10am to 8pm · Sat 10am to 5pm · Sun closed