Healer for full-face dermal repair
2ml black box for general skin quality. Reduces fine lines, improves dermal hydration. Course of 3 sessions, 4 weeks apart.
FOR DULL SKIN, FINE LINES, OR EARLY DERMAL THINNING
A Rejuran skin booster alone is rarely enough. We layer it with peptides.
Rejuran Healer is the polynucleotide base. Dr Samantha adds Teosyal RD-1 hyaluronic acid and amino acids to extend the glow. The combination lasts longer than Rejuran alone in her clinical observation over five years.
From SGD 500
TREATMENT MENUSGD 380SGD 600SGD 500SGD 600SGD 800SGD 1500
Pricing for every variant.
First time
Single-session Polynucleotide Healer (Rejuran Healer 2ml, full face)
Rejuran Healer 2ml (full face)
Rejuran I 1ml (under-eye)
Rejuran S 1ml (acne scar)
Nucleofill Strong 1.5ml (alt polynucleotide)
Nucleofill Strong 3ml
Rejuran polynucleotide skin booster variants and what each treats
What has changed in Rejuran since it launched 12 years ago
Rejuran patients usually arrive with dull skin, fine lines, or under-eye thinness, and the question of which variant fits. Rejuran is a polynucleotide skin booster derived from salmon DNA fragments, also called PDRN (polydeoxyribonucleotide), the most-recognised polynucleotide signal in the dermis. Three variants sit on the Nexus menu.
- the booster (black box, 2ml): full-face dermal repair. The most-prescribed Rejuran for general skin quality, fine lines, post-acne dullness.
- Rejuran I (red box, 1ml): under-eye specific. Lower viscosity, calibrated for the thin dermis around the orbital bone.
- Rejuran S (1ml syringe): acne scar variant. Paired with Pico laser ablation in the same session for ice-pick and rolling scars.
Nucleofill Strong is an Italian polynucleotide of similar class. Dr Samantha describes it as 'kind of like Rejuven, but Angmo version'. Available at Nexus when patients request it; the published safety and efficacy data on polynucleotide injection singapore patients receive at scale comes from the Rejuran line.
Why Teosyal RD-1 plus Rejuran Healer outperforms Rejuran alone
Dr Samantha's flagship full-face protocol is the Signature Glow Booster on /skin-booster: the booster is the base ingredient, then she adds hyaluronic acid (Teosil RD-1), peptides, amino acids, and trace anti-inflammatory components. Total volume is around 6ml. The mixing is what differentiates her layered approach from a one-syringe session.
Why 15mg/ml hyaluronic acid depth layers make the difference in a Rejuran skin booster
The most common patient frustration is 'I did 3 sessions and barely saw a difference.' Dr Samantha's read on this is honest: a polynucleotide skin booster covers dermal quality, not a complete protocol on its own. The dermal repair is real; the surface glow social media showcases comes from layered actives, not the polynucleotide alone.
If you specifically want a Rejuran-only protocol because the brand has been recommended to you, Dr Samantha will deliver the booster 2ml as a standalone session. Set expectations: visible result is dermal-quality improvement over 6 to 12 weeks for rejuran patients; individual results vary, and a same-week glow is not realistic.
How long Rejuran skin booster results last and why maintenance matters
the booster is not one protocol. The variant changes per concern, and for full-face skin quality the layered Signature Glow Booster usually outperforms a single-ingredient session for anyone who wants visible results in weeks rather than months.
Three patient profiles where solo the booster is the right pick:
- Strong personal preference for single-ingredient protocols and no other actives in the dermis.
- Under-eye crescent only. The 1ml under-eye variant is calibrated for that depth and area.
- Acne-scar work. Rejuran S paired with Pico ablation in the same session is the protocol of choice.
For everyone else, Dr Samantha's Signature Glow Booster on /skin-booster lands closer to what TikTok showed.
Is Rejuran the right tool for your skin?
An honest filter before booking. The profiles below see clean fit; others see partial fit at best.
Suitable for
Rejuran fits well
- Dull dermal quality, fine lines, post-acne textural improvement
- Under-eye thinness with visible vessel-shadow (Rejuran I)
- Active or recovering acne scarring (Rejuran S + Pico ablation)
- Patients who prefer single-ingredient regenerative protocols
- Asian skin with Fitzpatrick III-V (no significant pigment risk)
Take care
Rejuran is not the right tool
- Severe structural laxity needing HIFU or surgery
- Pigmentation as the dominant concern (Pico Laser is the right tool)
- Deep tear-trough hollow (filler is the right tool, not Rejuran I)
- Patients seeking a single-week dramatic glow (set expectations: 4 to 12 weeks)
- Pregnancy or breastfeeding (HCSA standard pause)
If your dominant concern is layered (skin quality plus laxity plus pigment), Dr Samantha will likely route you to her Signature Glow Booster on /skin-booster, which carries Rejuran Healer plus other actives in one session.
What a Rejuran polynucleotide skin booster session at Nexus involves
- Step 1, 20 min
Diagnostic consultation
Dr Samantha confirms the concern and the matched variant: Healer for face, I for under-eye, S for acne scar. Photos taken for the patient record.
- Step 2, 10 min
Numbing + skin prep
Topical anaesthetic for 8 to 10 minutes. Skin cleansed and marked at the placement zones.
- Step 3, 15 min
Injection
Dr Samantha personally delivers the polynucleotide via microneedle technique. Multiple shallow placements across the treatment zone.
- Step 4, 5 min
Cool down + aftercare brief
Cold compress, brief on the 48-hour aftercare window, follow-up appointment set if a course is recommended.
Total chair time around 50 minutes. Dr Samantha personally delivers every polynucleotide injection singapore patients receive at the clinic.
Rejuran polynucleotide skin booster sessions and results
Sessions and durability
| Variant | Sessions | Interval | Duration of results |
|---|---|---|---|
| Healer (full face) | 3 sessions | 4 weeks apart | 6 to 12 months |
| I, under-eye | 3 sessions | 4 weeks apart | 6 to 9 months |
| S, acne scar | 4 to 6 sessions | 4 weeks apart, paired with Pico | Long-lasting improvement with Pico maintenance (individual results vary) |
| Nucleofill Strong | 2 to 3 sessions | 4 weeks apart | 6 to 9 months |
| Signature Glow Booster (face) | 3 sessions | 4 weeks apart | 8 to 12 months |
Durability depends on age, skin tone, sun exposure, and aftercare. Most patients hold results with one or two maintenance sessions a year.
Rejuran skin booster side effects and what to expect after a session
Polynucleotide singapore patients tolerate this well. Most effects are mild and transient.
Worth knowing
Common (most patients)
- Mild redness for 1 to 2 hours post-session, settles without intervention
- Pinprick injection points visible for 4 to 12 hours
- Slight tenderness over treated zones for 12 to 24 hours
- Light bruising in 1 in 5 patients, clears in 3 to 5 days
Take care
Rare (under 5%)
- Larger bruising at vascular zones, resolves in 7 to 10 days
- Mild swelling lasting 24 to 48 hours, responds to cold compress
- Localised tenderness past 72 hours, message Dr Samantha for review
- Allergic reaction to a component (extremely rare in Rejuran; salmon-DNA derivation not problematic in fish-allergy patients per published data)
If you notice persistent pain, asymmetric swelling, or worsening tenderness past 72 hours, contact Dr Samantha. Long-term complications are very rare with calibrated technique.
Aftercare after a Rejuran polynucleotide booster session
Aftercare for polynucleotide skin booster singapore patients decides how well the polynucleotide remodelling holds. The pinprick zones need calm and barrier care.
- Day 0 to 2
Calm the injection points
Cold compress 5 minutes every 2 hours for the first day. No makeup over the injection points for 12 hours. Avoid strenuous exercise, alcohol, and saunas for 48 hours.
- Day 3 to 7
Restore the barrier
Switch back to a barrier-supporting moisturiser. Daily SPF 50 across the treated zone is non-negotiable. Skip retinol and acid actives until day 7.
- Week 2 onwards
Daily care matters more than any single product
Polynucleotide remodelling continues for 6 to 12 weeks. Daily aftercare and sun protection compound the result. Visible improvement at week 3 keeps progressing to month three.
Benefits of Dr Samantha's polynucleotide booster approach
Six clinical benefits stand out for patients on this protocol:
- Variant-matched: Healer for face, I for under-eye, S for acne scar. not one-size-fits-all.
- Doctor-delivered: Dr Samantha personally injects every polynucleotide session, not a therapist.
- Honest assessment first: Dr Samantha will tell you if a single-ingredient protocol is not the right fit for your concern.
- Combination-friendly: Rejuran S is part of the locked acne-scar protocol with Pico ablation.
- Asian-skin calibrated: rejuran polynucleotide has over a decade of clinical use in SG patients.
- Course-and-maintain: most patients hold results with one or two maintenance sessions a year after a course of 3.
Common Rejuran questions before booking
YOUR CONSULTATION
One assessment with Dr Samantha.
Twenty minutes with Dr Samantha. Consultation SGD 80, fully credited toward any treatment that follows.
111 Somerset Road, #03-19, TripleOne Somerset, Singapore 238164
Mon to Fri 10am to 8pm · Sat 10am to 5pm · Sun closed